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Suppliers for
LEE011 succinate
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Properties | CAS |
1374639-75-4 | Formula |
C23H30N8O.C4H6O4 |
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3 Registered suppliers
Molecular Formula: C27H36N8O5 Molecular Weight: 552.62534
Description : LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. - Molecular Weight :552.63
- Purity :> 98%
Molecular Formula : C27H36N8O5 Canonical SMILES : CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O InChI : InChI=1S/C23H30N8O.C4H6O4/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30;5-3(6)1-2-4(7)8/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28);1-2H2,(H,5,6)(H,7,8) InChIKey : NHANOMFABJQAAH-UHFFFAOYSA-N Synonyms : Ribociclib succinate; LEE 011 succinate; LEE-011 succinate
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Last update 2024-05-03
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